Concurrent and simultaneous polydrug use: latent class analysis of an Australian nationally representative sample of young adults.

Background: Alcohol use and illicit drug use peak during young adulthood (around 18-29 years of age), but comparatively little is known about polydrug use in nationally representative samples of young adults.Drawing on a nationally representative cross-sectional survey (Australian National Drug Strategy Household Survey), this study examines polydr

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Exploring the Spatial Structural and Optimization Modes of the Tourism Economy in Beibu Gulf Urban Agglomeration

The strategic position of the Beibu Gulf urban agglomeration has become increasingly prominent in terms of national economic development.In this paper, we propose the life cycle theory of urban agglomerations from the perspective of tourism-economic linkages and study the evolution of tourism-economic linkages and the spatial structure of emerging

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Measuring the optical properties of IceCube drill holes

The IceCube Neutrino Observatory consists of 5160 digital optical modules (DOMs) in a cubic kilometer of deep ice below the South Pole.The DOMs record the Alternator Controller Cherenkov light from charged particles interacting in the ice.A good understanding of the optical properties of the ice is crucial to the quality of the event reconstruction

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Membrane depolarization is required for pressure-dependent pulmonary arterial tone but not enhanced vasoconstriction to endothelin-1 following chronic hypoxia

Enhanced vasoconstriction is increasingly identified as an important contributor to the development of GLOSSY LIPSTICK ROSE FALLS #516 pulmonary hypertension.Chronic hypoxia results in enhanced Rho kinase mediated Ca 2+ sensitization contributing to pressure-dependent pulmonary arterial tone as well as augmented vasoconstriction to endothelin-1 and

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